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. Author manuscript; available in PMC: 2012 Sep 9.
Published in final edited form as: J Mol Biol. 2011 Jul 12;412(1):43–54. doi: 10.1016/j.jmb.2011.07.004

Figure 4. Sequences of Neu-related peptides.

Figure 4

Sequences of Neu/WT and Neu/V664E are shown at the top. Six dimeric sequences (Neu-Pos1 through Neu-Pos6) were identified in the screen. One of the seven sequences (Neu-Pos4) was identified twice independently. At the bottom are two random sequences from two beads out of the thousands of library members that were negative for dimerization in the screen (Neu-Ran1 and Neu-Ran2). In parenthesis is the statistical significance of the difference in activation in mammalian cells, relative to Neu/V664E, compared to the wild-type sequence, relative to Neu/V664E (ns=not significant, p> 0.05).