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. Author manuscript; available in PMC: 2012 Sep 9.
Published in final edited form as: J Mol Biol. 2011 Jul 12;412(1):43–54. doi: 10.1016/j.jmb.2011.07.004

Table 1.

Relative activation of Neu chimeras containing the indicated transmembrane domains. Activation was measured in triplicate, as described in the text, and normalized to the activation of the mutant Neu/V664E receptor. Uncertainties are standard errors and N=3 for all measurements.

Receptor Sequence Activation/NeuV664E
Mean +/− SE (N=3)
Neu/V664E graphic file with name nihms311310t1.jpg 1
Neu-Pos4 graphic file with name nihms311310t2.jpg 0.860 +/− 0.023
Neu-Pos2 graphic file with name nihms311310t3.jpg 0.779 +/− 0.015
Neu-Pos1 graphic file with name nihms311310t4.jpg 0.681+/− 0.011
Neu-Ran2 graphic file with name nihms311310t5.jpg 0.540 +/− 0.054
Neu-Ran1 graphic file with name nihms311310t6.jpg 0.454 +/− 0.060
Neu-Pos3 graphic file with name nihms311310t7.jpg 0.361 +/− 0.040
Neu-Pos6 graphic file with name nihms311310t8.jpg 0.345 +/− 0.041
Neu-Pos5 graphic file with name nihms311310t9.jpg 0.301 +/− 0.058
Neu WT graphic file with name nihms311310t10.jpg 0.281 +/− 0.051