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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Nanotechnology. 2011 May 17;22(26):265101. doi: 10.1088/0957-4484/22/26/265101

Figure 4.

Figure 4

In vivo efficacy of PEG-PIMA-Cisplatin nanoparticle in a syngeneic 4T1 murine breast tumor. (A) graph shows the tumor growth delay following treatment with free cisplatin (Cis) or cisplatin nanoparticle at 3mg/kg dose equivalent of cisplatin. The arrows depict the days on which the animals were injected with the drugs. (B) Cross-sections of tumors TUNEL-labeled for apoptosis. Low magnification (10×) images are shown to depict a large cross section. (C) Graph shows the biodistribution of platinum when administered as cisplatin or cisplatin nanoparticle. All data shown are mean ± SEM from n>4 per data point.