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. 2001 May 12;322(7295):1145. doi: 10.1136/bmj.322.7295.1145

Table 3.

Relation between headache in childhood and main outcomes at age 33. Values are odds ratios (95% confidence intervals) unless stated otherwise. Odds ratios refer to baseline group for each category of headache in childhood. Model 1 controls for sex and social class only, model 2 controls additionally for all variables in childhood, and model 3 controls additionally for all variables in childhood and psychiatric morbidity

No of participants exposed No (%) of cases Model 1 Model 2 Model 3
Multiple physical symptoms
 No childhood headache 5631 456 (8.1) 1.00 1.00 1.00
Headache 1153 164 (14.2) 1.85 (1.52 to 2.24) 1.77 (1.46 to 2.14) 1.61 (1.31 to 1.99)
Recurrent headache 253 36 (14.2) 1.82 (1.26 to 2.63) 1.69 (1.17 to 2.45) 1.67 (1.12 to 2.49)
χ2=35.9, P<0.001 χ2=29.2, P<0.001 χ2=20.2, P<0.001
Headache
 No childhood headache 5657 690 (12.2) 1.00 1.00 1.00
Headache 1163 247 (21.2) 1.92 (1.63 to 2.26) 1.87 (1.58 to 2.20) 1.79 (1.51 to 2.12)
Recurrent headache 253 61 (24.1) 2.30 (1.69 to 3.12) 2.22 (1.63 to 3.02) 2.22 (1.62 to 3.06)
χ2=69.4, P<0.001 χ2=62.9, P<0.001 χ2=54.6, P<0.001
Psychiatric morbidity
 No childhood headache 5615 718 (12.8) 1.00 1.00 Not applicable
Headache 1148 211 (18.4) 1.51 (1.27 to 1.79) 1.17 (1.00 to .137)
Recurrent headache 252 43 (17.1) 1.38 (0.98 to 1.93) 1.24 (0.91 to 1.68)
χ2=18.2, P<0.001 χ2=13.6, P<0.001