Figure 8.
Representative flow cytometric analysis of hepatocytes from experimental animals. Vehicle: hepatocytes from normal animals, AEPD: hepatocytes from the animals treated with AEPD only; CCl4: hepatocytes from the CCl4 intoxicated animals; AEPD + CCl4: hepatocytes from the animals treated with AEPD prior to CCl4 intoxication; CCl4 + AEPD: hepatocytes from the animals treated with AEPD post-CCl4 intoxication, Recovery: hepatocytes from the animals of recovery group and NaAsO2: hepatocytes from the NaAsO2 intoxicated (100 ppm in drinking water, 10 weeks) animals (Positive control). Dual parameter dot plot of FITC-lebelled Annexin V fluorescence (x-axis) versus PI-fluorescence (y-axis) has been shown in logarithmic fluorescence intensity. Quadrants: lower left, live cells; lower right, apoptotic cells; upper left, necrotic cells. Data are representative of three independent experiments.