Table 6.
Status of the thiol-based antioxidant in the liver tissue of the CCl4- and AEPD-treated animals.
| Animal groups | GSH | GSSG | Total thiols |
|---|---|---|---|
| Vehicle | 29.53 ± 1.52(a) | 3.45 ± 0.19(a) | 315.31 ± 15.76(a) |
| AEPD | 25.74 ± 1.29(a) | 3.51 ± 0.18(a) | 305.25 ± 15.31(a) |
| CCl4 | 8.34 ± 0.45(b) | 5.75 ± 0.28(b) | 155.89 ± 7.85(b) |
| AEPD + CCl4 | 21.45 ± 1.09(a),(c) | 3.85 ± 0.19(a) | 255.34 ± 12.74(a) |
| CCl4 + AEPD | 18.74 ± 0.95(c) | 4.01 ± 0.21(a) | 275.55 ± 13.79(a) |
| VitC + CCl4 | 23.45 ± 1.21(a) | 3.69 ± 0.18(a) | 297.31 ± 14.92(a) |
| Recovery | 9.15 ± 0.49(b) | 5.55 ± 0.27(b) | 168.52 ± 8.45(b) |
GSH—nmol mg−1 protein; GSSG—nmol mg−1 protein and total thiols—nmol mg−1 protein. Data are mean ± SD, for six animals per group and were analyzed by one-way ANOVA, with Student-Newman-Keuls post hoc tests. Differences were attributed at P < .05, and homogeneous subgroups share common superscripted letters.