Table 1.
Characteristics of subjects according to Pneumocystis colonization status
| Subject Characteristics | Pc+ (n=8) | Pc− (n=11) |
|---|---|---|
| Male, n (%) * | 8 (61.5) | 5 (38.5) |
| Caucasian, n (%) | 8 (100) | 11 (100) |
| Age, median (range) | 65 (52–74) | 61 (55–69) |
| Pack years, median (range) | 42 (30–80) | 60 (25–106) |
| Inhaled corticosteroids, n (%) | 6 (46.1) | 7 (53.5) |
| Systemic steroid use, n (%) | 3 (37.5) | 5 (62.5) |
| Current macrolide use, n (%) | 0 | 2 (18.2) |
| Prior pneumonia, n (%) | 6 (75.0) | 11 (100) |
| Environmental exposures, n (%) ** | 7 (87.5) | 10 (90.9) |
| Post bronchodilator FEV1, median (range) | 0.68 (0.58–2.07) | 0.67 (0.41–1.41) |
| FEV1 percent predicted, median (range) | 19.9 (13.8–63.4) | 22.7 (14.4–35.7) |
| DLco percent predicted, median (range) | 27.1 (16.5–34.3) | 31.5 (17.3–45) |
*
p=0.02
**
asbestos, berrylium, coal dust, cadmium, cobalt, diesel engine exhaust fumes, silica
Abbreviations: DLco, diffusing capacity for carbon monoxide; FEV1, forced expiratory volume in one second; Pc, Pneumocystis