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. Author manuscript; available in PMC: 2012 Sep 15.
Published in final edited form as: Biol Psychiatry. 2011 May 14;70(6):583–592. doi: 10.1016/j.biopsych.2011.03.035

Table 1. Adolescent cocaine exposure leads to downregulation of plasma membrane and synaptic genes in the amygdala.

Microarray analysis revealed a group of 36 genes classified as “synaptic” or “plasma membrane part” that were downregulated in animals that received cocaine during adolescence. Shown are the probe set IDs, gene name, accession number, fold changes, and p-value (based on log2-transformed data). Vehicle n=6; cocaine n=7.

Probe ID Gene name Accession Fold
change
P value
1370121_at Add1: adducin 1 (alpha) NM_016990 −1.19 4.27E-02
1368534_at Adra1d: adrenergic receptor, alpha 1d NM_024483 1.71 4.62E-02
1370621_at Cd3z: CD3 antigen, zeta polypeptide D13555 −1.13 3.10E-02
1369559_a_at Cd47: CD47 antigen (Rh-related antigen, integrin-associated signal
transducer)
NM_019195 −1.18 2.50E-02
1369025_at Cd5: CD5 antigen NM_019295 −1.11 3.28E-02
1373102_at Cdh13: cadherin 13 BI282750 −1.19 6.45E-03
1369112_at Chrm3: cholinergic receptor, muscarinic 3 M18088 −1.17 4.30E-02
1373067_at Ctnnb1: Catenin (cadherin associated protein), beta 1 AI102738 −1.18 4.84E-02
1370625_at Faim2: Fas apoptotic inhibitory molecule 2 AF044201 −1.21 3.06E-02
1398246_s_at Fcgr3: Fc receptor, IgG, low affinity III NM_053843 −1.15 4.41E-02
1369267_at Gabrg3: gamma-aminobutyric acid A receptor, gamma 3 NM_024370 −1.25 1.85E-02
1370590_at Gpsm1: G-protein signalling modulator 1 (AGS3-like) AF107723 −1.17 4.08E-02
1377546_at Gria4: Glutamate receptor, ionotropic, 4 BF397279 −1.31 1.48E-02
1371180_a_at Grm1: glutamate receptor, metabotropic 1 Y18810 −1.16 4.15E-02
1378625_at Grm8: Glutamate receptor, metabotropic 8 BF392502 −1.19 2.01E-03
1368783_at Icos: inducible T-cell co-stimulator NM_022610 −1.13 4.78E-02
1368979_at Kalrn: kalirin, RhoGEF kinase NM_032062 −1.11 3.53E-02
1370078_at Lin7b: lin-7 homolog b (C. elegans) NM_021758 −1.13 3.10E-03
1384190_at Mapk8ip3: mitogen-activated protein kinase 8 interacting protein 3 BF553848 −1.17 2.53E-02
1395927_at Pdzk1: PDZ domain containing 1 BE116199 −1.12 3.12E-02
1388966_at P2ry1: purinergic receptor P2Y, G-protein coupled 2 BM388250 −1.13 4.61E-02
1393207_at Rab35: RAB35, member RAS oncogene family BF566116 −1.12 4.31E-02
1369338_at Robo1: roundabout homolog 1 (Drosophila) NM_022188 −1.17 4.98E-02
1369054_at Rph3a: rabphilin 3A homolog (mouse) NM_133518 −1.27 2.29E-02
1368907_at Scamp5: secretory carrier membrane protein 5 NM_031726 −1.14 4.45E-03
1368445_at Shank1: SH3 and multiple ankyrin repeat domains 1 BE105448 −1.17 1.32E-02
1369715_at Slc6a11: solute carrier family 6, member 11; GABA transporter M95763 −1.3 5.00E-02
1387693_a_at Slc6a9: solute carrier family 6, member 9; glycine transporter M95413 −1.3 2.49E-02
1368896_at Smad7: MAD homolog 7 (Drosophila) NM_030858 −1.14 1.47E-02
1381263_at Slc27a4: solute carrier family 27 (fatty acid transporter), member 4 H33747 −1.15 4.24E-02
1370840_at Stxbp1: syntaxin binding protein 1 NM_013038 −1.11 7.16E-03
1369423_at Syn3: synapsin III NM_017109 −1.26 1.45E-02
1387527_at Syngr1: synaptogyrin 1 NM_019166 −1.17 4.07E-02
1370514_a_at Syt7: synaptotagmin VII AI713274 −1.13 1.48E-02
1378407_at Trim9: tripartite motif-containing 9 BF401415 −1.23 2.07E-02
1369330_at Unc13a: unc-13 homolog A (C. elegans) NM_022861 −1.12 1.74E-02
1384158_at Unc13c: unc-13 homolog C (C. elegans) AW522416 −1.2 4.86E-02
1387716_at Utrn: utrophin NM_013070 −1.32 2.47E-02