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. 2010 Dec 10;183(8):1103–1111. doi: 10.1164/rccm.201004-0620OC

TABLE 2.

COST PARAMETERS IN 2008 U.S. DOLLARS AND DATA SOURCES

Item Resource Use Unit Cost
Total cost of IPT per additional patient $16.97
 Nurse screening time (15 min during six follow-up visits) 90 min $13.81
 Isoniazid (INH) 6 mo 182 DDD $2.31
 Pyridoxine (B6) months 182 DDD $0.85
Total cost per CXR $13.50
 Equipment costs per CXR $2.86
 Film cost per CXR $2.94
 Radiographer: administer CXR 20 min $2.92
 Medical officer: reading CXR 10 min $4.78
Total cost per patient for DOTS (pan-susceptible) $288.28
 Pharmacist: observation (10 min daily for 182 d) 1,820 min $278.92
 Standard 182 d of DOTS treatment (HRZE2HR4) 182 DDD $9.36
Total cost per patient for DOTS (INH-R) $294.40
 Pharmacist: observation (10 min daily for 182 d) 1,820 min $278.92
 Standard 182 d of DOTS treatment (HRZE6) 182 DDD $15.48
Total cost per patient for second-line DOTS (MDR TB) $3,865.61
 Nurse: observation and injection (10 min daily for 6 mo) $279.23
 Pharmacist: observation (10 min daily for 18 mo) $838.28
 Medical officer: medical evaluation (20 min monthly for 24 mo) $229.24
 6 mo of Amik+Ethio+PZA+Cipro and 18 mo of Ethio+Cipro $2,518.86
Total cost of evaluation for TB disease $23.40
 Nurse: intake 15 min $2.30
 Medical officer: clinical evaluation 25 min $11.94
 Lab technician: performance of three sputum smears 15 min $2.30
 Materials for sputum smear microscopy 3 $6.86
Total cost per patient for patient tracking $30.39
 Assistant health educator: time spent tracking patient 6 h $17.53
 Telephone airtime $2.14
 Vehicle use cost $10.71

Definition of abbreviations: Amik = amikacin; Cipro = ciprofloxacin; CXR = chest X-ray; DDD = daily defined dose; DOTS = directly observed anti-TB therapy short course; Ethio = ethionamide; HR4 = isoniazid plus rifampicin for 4 months; HRZE2, HRZE6 = isoniazid plus rifampicin plus pyrazinamide plus ethambutol for 2 and 6 months, respectively; INH-R = isoniazid resistant; IPT = isoniazid preventive therapy; MDR TB = multidrug-resistant tuberculosis; PZA = pyrazinamide.

Salaries are based on the following hourly wages in Botswana: nurse (C4–C1 pay grade), $9.21; radiographer (C4–C2 pay grade), $8.77; medical officer (D4–D2 pay grade), $28.65; laboratory technician (C4–C2 pay grade), $9.20; and assistant health educator (B1–B5 pay grade), $2.92 [reported in Adjustment of Salary Scales and Review of Allowances 2008 DP 2/5 XI (115) 02/22/2008. Public Service Management Directive No. 1 of 2008].