Table 4.
Predictor variable | Number of survivors (N/%) | Number of non-survivors (n/%) | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|---|---|
O.R. (95% C.I.) |
P-value | O.R. (95% C.I.) |
P-value | |||
Age (years) | ||||||
< 40 | 56 (73.7%) | 20 (26.3%) | ||||
≥ 40 | 2(7.7%) | 24 (92.3%) | 3.4 (2.8-5.2) | 0.012 | 5.8(3.7-17.3) | 0.002 |
Sex | ||||||
Male | 54 (47.4%) | 40(42.6%) | ||||
Female | 4 (50.0%) | 4 (50.0%) | 0.2 (0.1-5.4) | 0.675 | 0.4 (0.3-2.1) | 0.986 |
Incubation period(days) (N = 88) | ||||||
< 7 | 24 (37.5%) | 40(62.5%) | ||||
≥ 7 | 20(83.3%) | 4 (16.7%) | 6.3(3.6-9.7) | 0.002 | 0.5(0.3-0.9) | 0.014 |
Period of onset (hours) (N = 65) | ||||||
< 48 | 11 (29.7%) | 26 (70.3%) | ||||
≥ 48 | 10 (35.7%) | 18 (64.3%) | 0.4 (0.2-2.6) | 0.561 | 1.7 (0.5-3.2) | 0.937 |
Prior immunization | ||||||
Yes | 16(66.7%) | 8 (33.3%) | ||||
No | 42(53.8%) | 36(46.2%) | 3.9 (0.4-6.2 | 0.068 | 0.9 (0.5-2.5) | 0.561 |
Admission pattern | ||||||
ICU | 48(57.1%) | 36 (42.9%) | ||||
Wards | 10 (55.6%) | 8 (44.4%) | 4.4(0.6-6.7) | 0.491 | 3.8(0.7-4.9) | 0.849 |
Type of tetanus | ||||||
Generalized | 56 (55.6%) | 43 (43.4%) | ||||
Cephalic | 1(50.0%) | 1 (50.0%) | 2.5 (0.9-3.1) | 0.067 | 1.7(0.2-5.4) | 0.082 |
Localized | 1(100%) | - | ||||
Severity of tetanus (N = 78) | ||||||
Moderate | 7(87.5%) | 1 (12.5%) | ||||
Severe | 27(38.6%) | 43 (61.4%) | 2.4(1.3-6.3) | 0.012 | 4.7(2.5-9.1) | 0.001 |
Debridement done | ||||||
Yes | 34 (63.0%) | 20 (37.0%) | ||||
No | 24 (50.0%) | 24 (50.0%) | 2.4(0.6-3.9) | 0.075 | 5.1(0.9-6.8) | 0.089 |
Tracheostomy done | ||||||
Yes | 14 (87.5%) | 2 (12.5%) | ||||
No | 44(51.2%) | 42(48.8%) | 3.1(1.4-7.3) | 0.011 | 4.9(2.3-8.1) | 0.004 |
Need for ventilatory support | ||||||
Yes | 26(81.3%) | 6(18.7%) | ||||
No | 32 (45.7%) | 38 (54.3%) | 1.7(1.1-4.5) | 0.032 | 0.2 (0.1-0.8) | 0.013 |
Complications | ||||||
Present | 35 (62.5%) | 21 (37.5%) | ||||
Absent | 23(50.0%) | 23 (50.0% | 3,9(0.5-4.3) | 0.063 | 1.6(0.4-6.2) | 0.911 |