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. 2011 Oct 1;15(7):1789–1797. doi: 10.1089/ars.2010.3769

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Copyright 2011, Mary Ann Liebert, Inc.

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FIG. 2. — PHD-1^−/− mice showed decreased infarct size and cardiomyocyte apoptosis after I/R. (A) The quantitative analysis from 6 different animals (n = 6) showed decreased infarct size in PHD1IR when compared to WTIR. (B) Representative digital micrographs showing cardiomyocyte apoptosis of PHD1IR and WTIR groups. (C) Quantitative analysis of cardiomyocyte apoptosis after I/R injury from 4 different animals in each group, in counts/100 high-power field (HPF). The apoptotic cardiomyocytes were significantly reduced in PHD1IR compared to WTIR. WTIR indicates WT animals subjected to I/R injury; PHD1IR, PHD-1^−/− animals subjected to I/R injury. *p ≤ 0.05, versus WTIR. I/R, ischemia/reperfusion. (To see this illustration in color the reader is referred to the web version of this article at www.liebertonline.com/ars).