FIG. 4.

Reduced APN stimulated AMP-activated protein kinase (AMPK)/acetyl-CoA carboxylase (ACC) activation occurred in HD mice. (A) Effect of adiponectin treatment on AMPKα2 phosphorylation determined by representative Western blots. (B) Effect of adiponectin treatment on ACC phosphorylation determined by representative Western blots. n = 5–8 hearts per group. ^**p < 0.01 versus sham control in the same diet group; ^$p < 0.05, ^$$p < 0.01 versus low dose gAPN-treated animals in the same diet group; ^&p < 0.05 between different diet groups with the same treatment.