FIG. 8.

Peroxynitrite was significantly blunted in HD-induced diabetic heart. (A) Nitrotyrosine content determined by ELISA (n = 10–13/group). ^**p < 0.01 versus sham control in the same diet group; ^#p < 0.05, ^##p < 0.01 versus vehicle-treated group in the same group; ^$$p < 0.01 versus low dose gAPN-treated animals in the same diet group. (B) A schematic illustration of the hypothesis tested in the current study. (To see this illustration in color the reader is referred to the web version of this article at www.liebertonline.com/ars).