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. Author manuscript; available in PMC: 2011 Aug 22.
Published in final edited form as: Brain Res. 2007 Jan 13;1142:28–36. doi: 10.1016/j.brainres.2007.01.028

Figure 2.

Figure 2

(A) Influence of water bath temperature on baseline withdrawal latencies in chronic morphine infused P17 rats. Rats were infused with morphine (●, 2 mg/kg/h) for 72-h from implanted osmotic minipumps. Baseline latencies were then obtained by testing individual groups of rats at different water bath temperatures. As the temperature of the water bath was increased, the baseline tail withdrawal latencies increased. n=6 rats per temperature.(B) Antinociceptive effects of morphine at different water bath temperatures. Rats were infused with morphine (▧, 2 mg/kg/h) for 72-h from implanted osmotic minipumps. Individual groups of P17 rats were then treated with morphine (100 mg/kg, s.c.) and then tested with different water bath temperatures 30-min later. As the temperature of the water bath was increased, the tail withdrawal latencies increased. n=6 rats per temperature.