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Tracking post-MI macrophage infiltration using Gd-liposomes. Gd-DTPA-enhanced inversion-recovery (IR) MRI demonstrates the region of infarction 2 days after MI (A, arrows). No myocardial enhancement was seen at day 2 post-MI before administering Gd-DTPA and after administering Gd-liposomes. (B). However, on day 4 post-MI (C), macrophages labeled with Gd-liposomes have infiltrated the infarct zone and show enhancement on IR images (arrows).
