Table 6.

Summary of test evaluation criteria to compare/contrast to utility of the three premorbid functioning estimates

Test Evaluation Criteria	Supporting Analysis	ANART	WASI Vocab	WASI Matrix	two-subtest WASI Combined
1. Evidence for test stability	Multivariate regression baseline model	√+	√−	√	√−
	Multivariate mixed longitudinal model	√	√	√	√
	SE for estimated two-year change	√+	√	√−	√−
	Test-retest reliability	√+	√	√−	√
2. Test relationships with variables that have known relationships with cognitive functioning	Pearson correlation with age	√	√	√	√+
	Pearson correlation with education	√	√	√	√
	Spearman correlation with gender	√	√	√+	√
	Contrast by geographic region*	√	√−	√	√−
3. Administration time	N/A	√+	√	√	√−

Note. ANART = American National Adult Reading Test; WASI = Wechsler Abbreviated Scale of Intelligence; Vocab = Vocabulary subtest; Matrix = Matrix Reasoning subtest; Combined = Combined subtest scores. Evidence for test stability is demonstrated by no differences between Huntington disease groups and controls on IQ test performance, smaller relationships between test performance and indices of disease progression, smaller SE, and higher test-retest correlations. In addition, “hold” measures should also have little to no relationship with age, education, gender, and region of testing.

√− = good; within range for standards generally accepted in the field, but lower/less strong relationships than the other premorbid functioning estimates

√=very good; within range for standards generally accepted within the field

√+= excellent; within range for standards generally accepted in the field, but higher/stronger relationships than the other premorbid functioning estimates

^*from multivariate mixed model