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Time (s) on the Rota-rod observed in mice after oral route treatment with Vehicle (control), iso-6-spectaline (0.1, 0.5 and 1.0 mg/ kg, p.o., SPEC) or DZP (2.0 mg/kg, i.p.). The motor response was recorded for the following 180 s after drug treatment. Values are mean ± S.E.M. for seven mice per group. *P < 0.001 as compared to control (Vehicle), one-way ANOVA followed by Student-Neuman- Keuls t-test
