Figure 4.
NR2A subunit-containing NMDARs mediate context fear memory retrieval by RSC. A, Retrieval of recent context fear memory was blocked by infusion of the preferential NR2A antagonist NVP, but not the specific NR2B antagonist Ro (NVP: n = 8; Ro: n = 8; Veh: n = 7; left), or the AMPAR antagonist CNQX (CNQX: n = 8; Veh: n = 7; right). B, Remote fear memory retrieval was similarly disrupted by NVP, but not Ro (NVP: n = 6; Ro: n = 6; Veh: n = 7; left) or CNQX (CNQX: n = 7; Veh: n = 8; right).