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Identifying single loci LOH status based on the genotypes of paired normal and tumor samples from the same individual
| Genotypes | Tumor |
||||
|---|---|---|---|---|---|
| AA | AB | BB | NoCall | ||
| Normal | AA | No-info | Mutation | Mutation | No-info |
| AB | LOH | RET | LOH | No-info | |
| BB | Mutation | Mutation | No-info | No-info | |
| NoCall | No-info | RET | No-info | No-info | |
LOH: loss of heterozygosity, RET: retention, No-info: Non-informative.
