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Structural conservation of the 5′- and 3′-ends of the MSL structure. Sequence variation was previously assessed using an alignment of 76 strains of domestic cat FIV. The ability of each strain of FIV to form this MSL structure was determined using this alignment. Grey nucleotides represent those which vary in sequence but maintain the ability to base pair in 100% of isolates. SLs 1–4 are not shown.
