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. 2011 May 5;39(15):6764–6774. doi: 10.1093/nar/gkr283

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© The Author(s) 2011. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Model of Sso7c4 interaction with a bent DNA. (A) Putative DNA-binding site of Sso7c4. Conserved residues appear on the same face corresponding to NMR chemical-shift perturbation data. The transformed surface is complementary to the bent DNA in charge and shape. (B) The DNA-binding surface of the Sso7c4 dimer was docked manually into the major groove so that the molecular 2-fold axis of the dimer was aligned with a local dyad of dsDNA. (C) The side view of Sso7c4 binding to bent DNA relates to the top view of that in (B) by 90° rotation around the horizontal axis.