Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Diagram of inducible Luciferase (Luci) Tetracycline response element (TRE) Survival motor neuron (SMN) transgenic construct and reverse tetracycline trans activator (rtTA) inserted into the ROSA26 locus with the floxed stop cassette removed (58). IRES, internal ribosome entry sequence; EGFP, enhanced green fluorescent protein; PminCMV, minimal cytomegalovirus promoter; Luc, Luciferase; SA, splice acceptor site; rtTA, reverse tetracycline trans activator; Dox, doxycycline.
