Table 4.
A subset of multi-pass hydrophobic integral membrane proteins identified using methanol-based buffers
| Acc No | Protein Name | Helicesa | GRAVYb | Cellular location |
|---|---|---|---|---|
| P12235 | ADP/ATP translocase 1 | 3 | 0.059 | Mitochondrion inner membrane |
| P00846 | ATP synthase a chain | 6 | 0.952 | Mitochondrion inner membrane |
| Q6UW11 | ATWD578 | 3 | 0.181 | Integral to membrane |
| Q9NX76 | CKLF-like MARVEL transmembrane protein | 3 | 0.458 | Membrane |
| Q9BUN8 | Derlin-1 | 5 | 0.386 | Endoplasmic reticulum membrane |
| Q8TCJ2 | Dolichyl-diphosphooligosaccharide--protein | 10 | 0.038 | Endoplasmic reticulum membrane |
| P46977 | Dolichyl-diphosphooligosaccharide--protein | 13 | 0.238 | Endoplasmic reticulum membrane |
| Q9BW60 | Elongation of very long chain fatty acids protein 1 | 7 | 0.352 | Endoplasmic reticulum membrane |
| P33947 | ER lumen protein retaining receptor 2 | 4 | 0.722 | Endoplasmic reticulum membrane |
| Q9H3K2 | Growth hormone-inducible transmembrane protein | 6 | 0.418 | Membrane |
| O75352 | Mannose-P-dolichol utilization defect 1 protein | 5 | 0.679 | Membrane |
| O14880 | Microsomal glutathione S-transferase 3 | 4 | 0.282 | Microsome membrane |
| Q13423 | NAD(P) transhydrogenase, mitochondrial precursor | 12 | 0.299 | Mitochondrion inner membrane |
| P61619 | Protein transport protein Sec61 subunit alpha isoform 1 | 10 | 0.563 | Endoplasmic reticulum membrane |
| O43760 | Synaptogyrin-2 | 4 | 0.168 | Membrane |
| P30536 | Translocator protein | 5 | 0.266 | Mitochondrion membrane |
| Q9UNL2 | Translocon-associated protein subunit gamma | 4 | 0.066 | Endoplasmic reticulum membrane |
| Q9BVC6 | Transmembrane protein 109 precursor | 5 | 0.541 | Nucleus outer membrane |
| P57088 | Transmembrane protein 33 | 3 | 0.429 | Membrane |
| Q96CP4 | Transporter 1, ATP-binding cassette, sub-family B | 7 | 0.142 | Integral to membrane |
| Q6RW13 | Type-1 angiotensin II receptor-associated protein | 3 | 0.482 | Endoplasmic reticulum membrane |
| Q9H1C4 | UNC93 homolog B1 | 12 | 0.095 | Membrane |
| Q8N357 | Uncharacterized protein C2orf18 precursor | 10 | 0.561 | Membrane |
| P27449 | Vacuolar ATP synthase 16 kDa proteolipid subunit | 4 | 1.041 | Vacuole membrane |
a
A number of transmembrane domains mapped by TMHMM algorithm.
b
A grand average of hydropathicity (GRAVY) index calculated for a given protein.