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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Exp Cell Res. 2011 Jun 22;317(16):2342–2352. doi: 10.1016/j.yexcr.2011.06.005

Figure 7. Bafilomycin treatment renders wild type cells resistant to BFA and augments the delayed BFA response in Cog-deficient cells in a GBF1-independent manner.

Figure 7

(Panel A) Wild type and Cog7-deficient fibroblasts were pretreated for 4 hr with 50 nM bafilomycin followed by BFA treatment (5 μg/mL) for either 20 or 40 min. The cells were stained for GBF1 and giantin and visualized by confocal microscopy. (Panel B) Quantitation of the percentage of cells with an ER staining pattern is shown. (Panel C) WT fibroblasts treated with and without 50 nM bafilomycin for 3 hr were stained for GBF1. Bar = 10 μm.