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. Author manuscript; available in PMC: 2012 Aug 15.
Published in final edited form as: Phytomedicine. 2011 Apr 21;18(11):998–1005. doi: 10.1016/j.phymed.2011.02.014

Fig. 8.

Fig. 8

Effects of Ro1138452 at the concentrations of 0.1 μM (n = 8), 1 μM (n = 8) and 3 μM (n = 5) on the inhibitory responses of schisandrin (10 μM) and cicaprost (10 nM) in isolated rat colon. The colon segments were pre-incubated with the prostacyclin receptor antagonist for 15 min before the addition of schisandrin or cicaprost. Ro1138452 attenuated the inhibitory response of cicaprost in a concentration-dependent manner (P < 0.001) while had no effect on schisandrin (P > 0.05). Values are expressed as mean ± S.E.M.. ***P < 0.001 compared to control.