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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: J Immunol. 2011 Jul 22;187(5):2626–2631. doi: 10.4049/jimmunol.1003930

Fig. 3. TLR2 KO or TLR4 KO mice are resistant to a lethal challenge of ConA.

Fig. 3

(a) Survival rates of TLR2 KO or TLR4 KO mice injected intravenously with a lethal dose of ConA (30 mg per kg body weight), combined with the data for WT mice shown in Fig. 2b. P values are as compared to WT mice treated with isotype control antibody. Data from 5 experiments. (b) TNFα, IL-6, IFNγ, IL-1β, KC, IL-10 and IL-12p70 levels in TLR2 KO, TLR4 KO or WT mouse plasma collected 2 h after the lethal challenge of ConA. Data for TNF and IL-6 from untreated WT mice are repeated from Fig. 2c. Data from 5 experiments.