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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: J Immunol. 2011 Jul 29;187(5):2162–2171. doi: 10.4049/jimmunol.1002906

Figure 5.

Figure 5

Complex Interaction Of KIR3DS1-Specific Residues Combine To Control HLA Recognition. HEK293T cells were transfected with 2 μg of plasmid containing FLAG tagged KIR3DS1 or the indicated double, triple or quadruple mutant and stained with PE-conjugated HLA tetramers. The mean fluorescence intensity of the tetramer stained cells is expressed as fold change over the fluorescence of unstained cells. Data shown are the averages of two independent experiments, error bars represent standard deviation.