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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Am J Kidney Dis. 2011 May 20;58(3):418–428. doi: 10.1053/j.ajkd.2011.03.018

Table 3.

Association of time-averaged serum albumin and all-cause, CV, and infection-related mortality in PD patients

Time-averaged
serum albumin
(g/dl)
HR (95% CI) Adjusted HR (95% CI)
All-Cause Mortality CV Mortality Infection-Related Mortality
< 3.0 5.80 (4.88–6.89) 6.23 (4.67–8.31) 7.16 (4.60–11.15)
3.00 – 3.19 4.40 (3.70–5.23) 4.83 (3.62–6.44) 5.34 (3.42–8.33)
3.20 – 3.39 3.21 (2.72–3.79) 3.18 (2.40–4.21) 3.89 (2.53–5.97)
3.40 – 3.59 2.45 (2.07–2.88) 2.79 (2.12–3.68) 2.45 (1.59–3.77)
3.60 – 3.79 1.83 (1.55–2.16) 2.07 (1.57–2.73) 1.54 (0.98–2.39)
3.80 – 3.99 1.37 (1.15–1.64) 1.34 (0.99–1.81) 1.44 (0.91–2.28)
4.00 – 4.19 1.00 (reference) 1.00 (reference) 1.00 (reference)
≥ 4.19 0.86 (0.63-1.17) 1.04 (0.64–1.71) 0.81 (0.37–1.81)

Using 12,171 PD patients with time-averaged serum albumin between 4.00 and 4.19 g/dl as the reference group. Data adjusted for albumin category by modality, quarter of entry into study cohort, age, gender, race and/or ethnicity, diabetes, dialysis vintage, primary insurance, marital status, ischemic heart disease, congestive heart failure, myocardial infarction, cardiac arrest, pericarditis, cardiac dysrythmia, cerebrovascular disease, peripheral vascular disease, current smoking, body mass index, serum total iron binding capacity, ferritin, creatinine, calcium, phosphorus, parathyroid hormone, alkaline phosphatase, hemoglobin, white blood cell count, and % lymphocyte

CV, cardiovascular; HR, hazard ratio; CI, confidence interval; PD, peritoneal dialysis.