Table 1.
Characteristics at the Time of Incident or Prevalent Hypercholesterolemia in HIV-infected Children
| Hypercholesterolemia
|
|||
|---|---|---|---|
| Characteristic | Prevalent (N=314) | Incident (N=240) | |
| Age (yr) | Median | 8.7 (6.1 11.3) | 10.3 (7.5, 12.8) |
| Race/ethnicity | White Non-Hispanic | 61 (19%) | 39 (16%) |
| Black Non-Hispanic | 170 (54%) | 129 (54%) | |
| Hispanic | 79 (25%) | 69 (29%) | |
| Asian, Pacific Islander | 1 (0%) | 1 (0%) | |
| Other/unknown | 2 (1%) | 2 (1%) | |
| More than one race | 1 (0%) | 0 (0%) | |
| Sex | Male | 157 (50%) | 126 (53%) |
| Female | 157 (50%) | 114 (48%) | |
| BMI z-score | Median | 0.34 (−0.31, 0.95) | 0.28 (−0.43, 1.04) |
| Diastolic BP > 90th %-ile | Yes | 32 (10%) | 11 (5%) |
| No | 261 (83%) | 206 (86%) | |
| Missing | 21 (7%) | 23 (10%) | |
| Systolic BP > 90th %-ile | Yes | 86 (27%) | 55 (23%) |
| No | 207 (66%) | 162 (68%) | |
| Missing | 21 (7%) | 23 (10%) | |
| HIV RNA (copies/ml) | 0–400 | 201 (64%) | 169 (70%) |
| 401–5000 | 49 (16%) | 46 (17%) | |
| 5001–50000 | 28 (9%) | 14 (6%) | |
| >50000 | 12 (4%) | 5 (2%) | |
| Missing | 24 (8%) | 11 (5%) | |
| CD4 percent | 0–14% | 16 (5%) | 6 (3%) |
| 15%–24% | 49 (15%) | 39 (16%) | |
| > 25% | 244 (78%) | 185 (77%) | |
| Missing | 6 (2%) | 11 (5%) | |
| Cholesterol (mg/dl) | Median | 242.5 (230, 266) | 236 (227, 251) |
| ARV Class | PI+NRTI(no NNRTI) | 172 (55%) | 132 (55%) |
| PI+NNRTI | 119 (38%) | 90 (38%) | |
| NNRTI+NRTI | 16 (5%) | 7 (3%) | |
| PI only | 3 (1%) | 3 (1%) | |
| NRTI only | 1 (0%) | 5 (2%) | |
| No ARV | 3 (1%) | 3 (1%) | |