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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: J Immunol. 2011 Jul 25;187(5):2148–2154. doi: 10.4049/jimmunol.1101180

Figure 4.

Figure 4

Maintenance of CD8 T cell responses to LM-OVA in CLP-treated Trail−/− and Dr5−/−B6 mice. Sham or CLP-treated WT, Trail−/− and Dr5−/− B6 mice were infected with 107 CFU attenuated LM-OVA 2 d post-surgery. A. Total CD8 T cell numbers in the spleen were determined 2 d post-surgery. On d 7 after infection, the number of Ag-experienced (B) and OVA257-specific (C) CD8 T cells in the spleen was determined. Panel C also shows representative flow plots measuring the frequency of IFN-γ-producing CD8 T cells with and without OVA257 restimulation in vitro. *p < 0.05 (Student’s t-test).