Table 1.
Arterial and venous blood analyses
| Analysis | Normal range | HIF2, n = 3 | Control, n = 6 | P value |
|---|---|---|---|---|
| Arterial Po2 (mmHg) | 83–105 | 105.0 ± 13.0 | 99.8 ± 9.5 | 0.52 |
| Arterial Pco2 (mmHg) | 35–45 | 32.1 ± 6.5 | 42.7 ± 3.7 | 0.01 |
| Arterial pH | 7.35–7.45 | 7.43 ± 0.04 | 7.38 ± 0.04 | 0.10 |
| Hemoglobin (g/dl) | 13–17 | 18.5 ± 1.8 | 16.1 ± 1.0 | 0.03 |
| Hematocrit (L/L) | 0.40–0.50 | 0.57 ± 0.05 | 0.49 ± 0.03 | 0.03 |
| Mean corpuscular volume (fl) | 83–105 | 84.6 ± 21.2 | 89.6 ± 2.8 | 0.56 |
| Serum iron (μM) | 14–31 | 17.0 ± 10.3 | 18.7 ± 4.6 | 0.75 |
| Ferritin (μg/L) | 20–300 | 75.8 ± 66.3 | 162.9 ± 93.2 | 0.27 |
| Transferrin (g/L) | 1.8–3.6 | 3.5 ± 0.2 | 2.7 ± 0.2 | 0.003 |
Values are means ± sd. P values compare the HIF2 patient group with the respective matched control participant group.