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(a–e) Wall thickness of afferent arterioles (AAs). Representative photographs of the α-smooth muscle isoform of actin immunohistochemistry from (a) sham, (b) AngII, (c) AngII+fasudil and (d) AngII+parthenolide. (f) Periodic acid-Schiff (PAS)-positive area as a marker of glomerular damage. Ni, nuclear factor-kappa beta inhibitor, parthenolide; Ri, Rho-kinase inhibitor, fasudil. *P < 0.05 compared with the sham group.
