Fig. 3.

A 61-year-old female with papillary thyroid carcinoma. (A) Ultrasonography shows an irregular and marked hypoechoic nodule with a shape that is taller than it is wide and internal mixed calcification in the right thyroid gland; this nodule was considered suspicious. (B) This fine-needle aspiration cytology was interpreted as suspicious for papillary thyroid carcinoma based on the presence of a rare cluster of follicular cells cytological overlapping and nuclear clearing and grooves (Papanicolaou stain ×200 original magnification). (C) This thyroidectomy specimen shows a few papillae with typical nuclear features of papillary carcinoma, such as nuclear pseudoinclusion, clearing and grooves, compatible with papillary carcinoma (H&E, ×400 original magnification).