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. 2011 Jun 7;7:496. doi: 10.1038/msb.2011.26

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Copyright © 2011, EMBO and Macmillan Publishers Limited

This is an open-access article distributed under the terms of the Creative Commons Attribution Noncommercial Share Alike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission.

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Distributions of Anatomic, Therapeutic and Chemical (ATC) top level classes among drug–disease associations in the gold standard (A) and the predicted associations (B). The relative ratio between the two distributions for each ATC class is shown in subfigure (C). ATC classes include: alimentary tract and metabolism (A), blood and blood forming organs (B), cardiovascular system (C), dermatologicals (D), genito urinary system and sex hormones (G), antineoplastic and immunomodulating agents (L), musculo-skeletal system (M), nervous system (N), respiratory system (R) and sensory organs (S).