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. 2011 Jul 19;7:515. doi: 10.1038/msb.2011.46

Table 1. Subsystems defined in the model iAF1260.

Alanine and aspartate metabolism
Alternate carbon metabolism*
(Metabolism of various carbon sources)
Anaplerotic reactions
(Supply of tricarboxylic acid cycle precursors)
Arginine and proline metabolism*
Cell envelope biosynthesis*
Citric acid cycle*
Cofactor and prosthetic group biosynthesis*
(Biosyntheses of flavin adenine dinucleotide (FAD), NAD(P), protoheme, pyridoxal 5-phosphate, riboflavin, siroheme, quinones, tetrahydrofolate, thiamin and undecaprenyl diphosphate)
Cysteine metabolism*
Folate metabolism
Glutamate metabolism
Glycerophospholipid metabolism*
(Biosyntheses of cardiolipin and phosphatidylethanolamine)
Glycine and serine metabolism*
Glycolysis/gluconeogenesis*
Glyoxylate metabolism
Histidine metabolism*
Inorganic ion transport and metabolism*
Lipopolysaccharide biosynthesis/recycling*
Membrane lipid metabolism*
(Fatty acid biosynthesis and oxidation)
Methionine metabolism*
(Metabolism of methionine and S-adenosyl-L-methionine)
Methylglyoxal metabolism*
Murein biosynthesis*
Murein recycling*
Nitrogen metabolism*
Nucleotide salvage pathway*
Oxidative phosphorylation
Pentose phosphate pathway*
Purine and pyrimidine biosynthesis*
Pyruvate metabolism*
Threonine and lysine metabolism*
Transport, inner membrane*
Transport, outer membrane
Transport, outer membrane porin*
tRNA charging
Tyrosine, tryptophan and phenylalanine metabolism*
Valine, leucine and isoleucine metabolism*