Table 5.

Administration of drugs that act on the histaminergic system into the amygdala and memory performance.

Species	Amygdala site	Behavioral task	Histaminergic modulator	Effect on memory	Reference(s)
Rat	Basolateral	Active avoidance	Histamine	↓	[144]
Rat	Basolateral	Contextual fear conditioning	H3 receptor antagonists (ciproxifan, clobenpropit and thioperamide)	↓	[154]
Rat	Basolateral	Contextual fear conditioning	H3 receptor agonists (RAMH or Immepip)	↑	[144, 155]
Rat	Basolateral	Contextual fear conditioning	H3 receptor agonist (proxifan)	↑	[156]

RAMH: (R)-(−)-alpha-methylhistamine.