Table 1.
Outcomes for Image Analysis of the Unstained Specimen and of Images Segmented by the Different Transforms and Algorithms
| Outcome | Unstained specimen | RVM2 DCA | RVM3 DCA | RVM2 β-NTF | RVM3 β-NTF | RVM2 HALS NMF | RVM3 HALS NMF | RVM2 NMU-ℓ1 | RVM3 NMU-ℓ1 |
|---|---|---|---|---|---|---|---|---|---|
| Sciatic nerve fiber (nervus ischiadicus) | |||||||||
| NTP | 55/55 | 50/51 | 52/51 | 48/48 | 53/55 | 50/49 | 54/54 | 48/49 | 58/58 |
| NFN | 0/0 | 4/4 | 4/2 | 5/5 | 2/1 | 5/55 | 1/2 | 4/4 | 1/1 |
| NFP | 27/27 | 11/11 | 30/32 | 20/19 | 42/40 | 20/22 | 20/19 | 27/25 | 29/30 |
| Spleen tissue | |||||||||
| NTP | 128/131 | 128/131 | 126/121 | 128/131 | Failed | 128/131 | Failed | 128/131 | 118/117 |
| NFN | 0/0 | 3/7 | 3/5 | 3/6 | Failed | 5/5 | Failed | 5/8 | 2/1 |
| NFP | 55/47 | 41/48 | 24/23 | 24/33 | Failed | 31/25 | Failed | 29/35 | 17/19 |
Results obtained independently by two pathologists are separated by a virgule mark.
Transforms: RVM2 and RVM3 (second-order and third-order rational variety mapping). Algorithms: DCA (dependent component analysis), β-NTF (β-divergence non-negative tensor factorization), HALS NMF (hierarchical alternating least-square non-negative matrix factorization), and NMU-ℓ1 (non-negative matrix underapproximation).
NFN, number of false negatives; NFP, number of false positives; NTP, number of true positives.