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. 2011 Sep 15;138(18):4063–4073. doi: 10.1242/dev.069195

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Fig. 5. — In situ hybridization in incisors of wild-type and Spry2^+/–;Spry4^–/– embryos. (A-F) Whole-mount RNA in situ hybridization for Shh in wild-type (A,C,E) and Spry2^+/–;Spry4^–/– (B,D,F) embryos at E11.5, E12.5 and E13.0. Red arrowheads point to the left incisor expression domain. (G,H) Whole-mount RNA in situ hybridization for Fgf4 in dissected incisor epithelia viewed from mesenchymal side of wild-type (G) and Spry2^+/–;Spry4^–/– (H) embryos at E14.5. EK, enamel knot; laCL, labial cervical loop; liCL, lingual cervical loop.