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Effect of SN79 on motor coordination in mice. Male, Swiss Webster mice that were trained to balance on a rotor rod were administered (i.p.) either saline or SN79 (1, 10 mg/kg). SN79 (10 mg/kg) caused motor incoordination in mice. The data are represented as mean ± S.E.M. A two-way ANOVA was conducted followed by Bonferroni’s post hoc tests. # p < 0.05, ## p < 0.01, ### p < 0.001, n = 10 per group
