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. 2011 Jun 8;13(3):427–437. doi: 10.1208/s12248-011-9284-7

Table I.

Definition of Symbols and Parameter Values Used in Simulations

Symbols Definition Value (range)
S(t) Number of susceptible individuals at time t
I(t) Number of infectious individuals at time t
I u(t) (I tr(t)) Number of untreated (treated) infectious at time t
R(t) Number of recovered individuals at time t
t 0 Time of introduction of the pathogen to the population Varied Varied
β 0 Background transmission rate Inline graphic
ε Related to the oscillation amplitude 0.35
γ u Recovery rate of untreated individuals 1 u = 3 (days)
γ tr Recovery rate of treated individuals 1 tr = 2 (days)
Inline graphic Proportion of susceptibles vaccinated [0, 1]
η Efficacy of vaccine [0, 1]
Inline graphic Proportion of susceptibles successfully vaccinated [0, 1]
f 0 Proportion of infections treated [0, 1]
t v Beginning times of vaccination Varied
σ Reduction in transmission due to treatment 0.5