Table 1.

Dose-response curve parameters

	EC50 (μm)	n (Hill coefficient)	n
Control	0.74 ± 0.01	1.58 ± 0.04	5–10
3 mm Asc	0.49 ± 0.01*	1.88 ± 0.07	5–10
Control	1.52 ± 0.04	2.24 ± 0.05	4
30 μm NEM	1.29 ± 0.02	2.24 ± 0.10	4
30 μm NEM + 3 mm Asc	0.75 ± 0.01	2.44 ± 0.19	4
Control	0.86 ± 0.10	2.58 ± 0.30	3
30 μm NEM	0.78 ± 0.09	2.32 ± 0.10	3
30 μm NEM + 2 mm DTT	0.74 ± 0.06	2.04 ± 0.08	3
H141D	1.76 ± 0.21	3.41 ± 0.61	10
H141D + 3 mm Asc	2.07 ± 0.32	2.94 ± 0.38	5
H141D + 30 μm NEM	1.40 ± 0.16	3.24 ± 0.16	4
H141D + 30 μm NEM + 3 mm Asc	1.46 ± 0.24	3.48 ± 0.28	4

Parameters of the D–R curves for GABA, performed for GABA ρ₁ wt and GABA ρ₁ H141D in the absence or presence of the different agents.

*p < 0.03.