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. 2011 Jun 3;30(14):2908–2919. doi: 10.1038/emboj.2011.182

Figure 4.

Figure 4

Decreased frequency of spontaneous mEPSCs in NL3R704C-mutant mice. (A, D) Sample traces of mEPSCs (A) and mIPSCs (D). (B, E) Cumulative probability plots of mEPSC (B) and mIPSC amplitudes (E). Insets display box plots of the amplitudes (numbers list number of cells recorded; mEPSC: WT=11 cells/4 mice; R704C=11 cells/4 mice; mIPSC: WT=13 cells/4 mice and R704C=11 cells/4 mice). (C, F) Cumulative probability plots of mEPSC (C) and mIPSC frequency, as measured by the inter-event intervals (F). Insets display box plots of the actual frequencies (n=same as for (B, E)). Data represent mean values±s.e.m. Statistical significance (*P<0.05) was evaluated with a KS-test (cumulative probability plots) and Student's t-test (box plots). Box plots represent median and inter-quartile range; vertical lines represent 10th and 90th percentiles.