FIG. 1.

Graphical illustration of how each of the 10 methods of glycemic variability assessment are calculated from a continuous glucose monitoring trace: average daily risk ratio (ADRR), continuous overlapping net glycemic action (CONGA), Glycemic Risk Assessment in Diabetes Equation (GRADE), High Blood Glucose Index (HBGI), Low Blood Glucose Index (LBGI), J-Index, Lability Index (LI), mean absolute glucose (MAG), mean amplitude of glucose excursions (MAGE), and mean of daily differences (MODD). In practice each method would independently assess the entire trace.