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. 2011 Aug 23;6(8):e23199. doi: 10.1371/journal.pone.0023199

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Tao et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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PTHrP induces a significant elevation of whole-blood ionized calcium levels in mice within three hours of injection with PTHrP (at day three and five). The whole-blood ionized calcium levels are lower in the FR167653-treated group than in the DW-treated group (control group) at day three (*: P<0.05). By day five, however, there was no significant difference between two groups.