Table 1. Treatment according to drug resistance patterns.

Resistance	Intensive phase	Continuation phase
S, E or ES	2 H R Z E	4 H R
MDR*	≥6 Cm-Ofx/Mx-Eto/Pto PAS Cs	18 Ofx/Mx Eto/Pto PAS Cs
H or HS	2H R Z E	7 R E Z
HE or HES	3 Cm/Km Ofx/Mx R Z	7 Ofx/Mx R Z
R or RS	3 Cm/Km Ofx/Mx E Z	12 Ofx/Mx E Z
RE or RES	3 Cm/Km Ofx/Mx H Z	12 Ofx/Mx H Z

E: ethambutol; S: streptomycin; H: isoniazid; MDR: multidrug resistance; Cm: capreomycin; Km: kanamycin; Ofx: ofloxacin; Mx: moxifloxacin; Eto: ethionamide; Pto: prothionamide; PAS: paramino salicylic acid; Cs: cycloserine.

*Empiric treatment further adapted to DST to 2nd line drugs.