Figure 2. Expression of HDMs and HMTs in normal human tissues and human cancer cell lines.

(A) Expression of HDMs and HMTs in normal human tissues. Gene-normalized expression values (log₂) of 26 HDMs and 11 HMTs are presented for eleven tissues (BioGPS database). (B) Expression of HDMs and HMTs in cancer cell lines. Gene-normalized (log₂) expression values were generated for eleven cell lines from GSK dataset. Expression level for each gene was described in terms of preferential expression and underexpression, which showed relative higher expression of multiple HDM and HMT genes in cancer cells compared to normal cells.