Figure 2.

Example drug exposure and adherence for a hypothetical patient.

A. Truth: dark solid lines=true consumption

B. Claims data “raw”: dark solid lines=drug use identified through pharmacy claims, dotted line=days in hospital identified through medical claims.

C. Claims data “raw” +50% days supplied grace period: dark solid lines=drug use identified through raw pharmacy claims, light solid lines=coverage added by applying a maximum 50% days supplied grace period to all gaps, dotted line=days in hospital identified through medical claims.

t₀=start of observation period, t₁=end of observation period; calculations only consider drug coverage during the observation period