Skip to main content
. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: J Immunol. 2011 Aug 3;187(5):2602–2616. doi: 10.4049/jimmunol.1101004

Figure 5. An adenoviral prime skews adjuvants towards the induction of cytophilic antibody isotypes.

Figure 5

BALB/c and C57BL/6 mice (n=5-6 / group) were immunized as described previously with AP and PPP regimes. IgG1 and IgG2a antibody responses were measured in the serum two weeks after the last immunization in response to (A) OVA, (B) EBA-175 and (C) MSP-119(QKNG allele) protein. Median and individualresponses are shown (A-C). IgG2a:IgG1 ratios were calculated for (D) OVA and (E) EBA-175 and log transformed. Mean responses are shown (D-E). The dotted line indicates the threshold for responses above background in (A). ND = no data.