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Effect of heparanase overexpression on MC degranulation.
Release of ß-hexosaminidase by peritoneal cells upon (A) Ionomycin + PMA or (B) anti-DNP-IgE + DNP-BSA treatment. The data are expressed as OD405nm values (ß-hexosaminidase activity) in the medium before and after activation. (C) Release of histamine by peritoneal cells upon anti-DNP-IgE + DNP-BSA treatment. Each symbol represents data from an individual animal.
