Table 1.
Effects of alcohol on the expression of FPS
| Treatment Group | Saline | 0.5 g/kg EtOH | 1.0 g/kg EtOH | 1.5 g/kg EtOH |
|---|---|---|---|---|
| HAP1 Male Fear | 81.5±22.2 | 56.0±15.5 | 69.7±19.4 | 33.3±13.8a |
| HAP1 Male Control | 12.1±6.4 | 7.4±11.2 | 23.7±12.6 | 13.4±15.9 |
| LAP1 Male Fear | 40.4±15.0 | 12.1±8.4 | 27.9±9.7 | 18.8±11.6 |
| LAP1 Male Control | 19.0±9.3 | 9.5±9.2 | 12.7±7.5 | 23.8±9.9 |
| HAP1 Female Fear | 75.7±18.8 | 62.4±25.5 | 60.8±28.4 | 23.9±12.7a |
| HAP1 Female Control | 10.9±11.2 | 18.4±11.1 | 39.7±16.8 | 11.5±10.9 |
| LAP1 Female Fear | 22.1±9.2 | 34.2±8.0 | 29.9±9.0 | 27.1±10.5 |
| LAP1 Female Control | 5.9±9.7 | −1.2±6.8 | 10.6±11.7 | −1.2±9.8 |
| HAP2 Male Fear | 82.6±15.2 | 70.4±11.9 | 32.4±8.6 | 52.7±13.2a |
| HAP2 Male Control | −6.1 ±5.8 | 2.5±8.9 | 3.4±7.3 | 16.7±7.5 |
| LAP2 Male Fear | 44.9±13.9 | 33.9±12.1 | 33.3±10.9 | 68.1±24.8 |
| LAP2 Male Control | 0.2±8.4 | 29.0±8.9 | 1.7±7.4 | −6.1±5.3 |
| HAP2 Female Fear | 39.0±10.2 | 38.3±8.6 | 54.5±8.1 | 42.0±12.1a |
| HAP2 Female Control | −2.5±6.1 | −13.3±5.2 | −0.1±5.7 | 6.2±6.8 |
| LAP2 Female Fear | 19.1±8.4 | 27.2±7.2 | 19.6±8.7 | 7.1±7.3 |
| LAP2 Female Control | −6.5±6.2 | −9.4±8.3 | 12.6±9.6 | −2.8±5.6 |
Mean (± SEM) % FPS data from Fig. 1 separately show the replicate lines 1 and 2 and male and female mice in fear-conditioned and control groups despite the lack of significant statistical interactions with these factors
a
Statistical comparisons collapsed across replicate and sex (p<0.05 saline vs. 1.5 g/kg group)